Endocrine Abstracts

Background: Hypovitaminosis D represents at present a worldwide public health problem. Recent studies have demonstrated the pleiotropic effects of vitamin D, in addition to its known actions on calcium-phosphorus metabolism. Among the several non-skeletal effects, a potential anti-inflammatory and immunomodulatory action has been suggested. Vitamin D deficiency has been reported in several chronic conditions associated with increased inflammation and deregulation of the immune...

Background: Many testosterone (T) formulations are now available for treating male hypogonadism. Intramuscular injectable T esters and transdermal T gel are the most commonly used in clinical practice. Transdermal T gel is often preferred by patients due to ease of use and reduced fluctuations in serum T compared to injectable esters. A daily dosage of 20 mg – 80 mg mimicking circadian profile is recommended to adequately treat hypogonadal men.Aim: ...